Zosyn is the brand name for which antibiotic combination?

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Study for the Anti-infective Medications Test. Work with interactive quizzes and detailed explanations. Master the concepts and increase your exam success rate by understanding various anti-infective drugs and their applications!

Multiple Choice

Zosyn is the brand name for which antibiotic combination?

Explanation:
Zosyn combines a penicillin with a beta-lactamase inhibitor to extend its spectrum. The penicillin is piperacillin, and the inhibitor is tazobactam. Tazobactam blocks beta-lactamase enzymes that would otherwise destroy piperacillin, allowing the antibiotic to work against a broader range of bacteria, including some that produce beta-lactamases. So, Zosyn is piperacillin plus tazobactam. The other options pair different drugs: amoxicillin with clavulanic acid is another penicillin/beta-lactamase inhibitor combo (Augmentin), Penicillin G with benzathine is a long-acting penicillin preparation, and cefazolin is a single cephalosporin antibiotic.

Zosyn combines a penicillin with a beta-lactamase inhibitor to extend its spectrum. The penicillin is piperacillin, and the inhibitor is tazobactam. Tazobactam blocks beta-lactamase enzymes that would otherwise destroy piperacillin, allowing the antibiotic to work against a broader range of bacteria, including some that produce beta-lactamases. So, Zosyn is piperacillin plus tazobactam. The other options pair different drugs: amoxicillin with clavulanic acid is another penicillin/beta-lactamase inhibitor combo (Augmentin), Penicillin G with benzathine is a long-acting penicillin preparation, and cefazolin is a single cephalosporin antibiotic.

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